Cyclophosphamide (CAS 50-18-0) is an antineoplastic medication used in chemotherapy and immunosuppressive therapy.
It is a synthetic, nitrogen, mustard-type alkylating agent. It is a fine white to off-white crystalline powder that is soluble in water and ethanol.
Workers may be exposed to cyclophosphamide during packaging, formulation, handling or administration of the drug, clean-up and disposal of chemotherapy drug waste, when assisting patients or when handling or cleaning linen.
Workers at risk of exposure include:
- medical practitioners
- veterinary nurses
- animal handlers
This guide provides information for those registered medical practitioners engaged by a PCBU to carry out or supervise health monitoring for workers. This guidance should be read in conjunction with the following: